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Clinical Phenotypes of ENPP1 Deficiency: GACI, ARHR2, and Beyond...

Saturday, September 28, 2024

Breakfast CME Satellite Symposium at the ASBMR, Metro Toronto Convention Center

255 Front Street West

Toronto, Ontario M4N 3N1

Satellite symposium held at the 2024 ASBMR Annual Meeting.  You must be registered for the ASBMR to attend this presentation. 

Schedule

* Times are EST
06:50 AM Breakfast Buffet
07:00 AM Welcome, Disclosures, Supporter Acknowledgement
07:05 AM GACI: Pathophysiology, Clinical Manifestations, Complications

Monoallelic Heterozygous ENPP1 Deficiency
ARHR2: Clinical Symptoms
Ossification of the Posterior Longitudinal Ligament (OPLL)
Current and Emerging Treatment Options, Monitoring, and Management
Strategies

08:15 AM Closing Comments, Audience Q&A
08:30 AM Adjourn

Presenters

David R. Weber, MD

Director
Center for Bone Health
Children’s Hospital of Philadelphia (CHOP)
Philadelphia, PA

Carlos Ferreira, MD

Head, Skeletal Genomics Unit
Metabolic Medicine Branch
NIH – National Human Genome Research Institute
Bethesda, MD

Accreditation

EXCEL Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

EXCEL Continuing Education designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Canadian CME: Through an agreement between the ACCME and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

The UEMS-EACCME®: European Union of Medical Specialists and European Accreditation Council for CME have mutual recognition agreements with the American Medical Association for live events and e-learning materials. European physicians can earn their ECMEC®s (European CME credits) by either attending a live presentation approved by an ACCME accredited provider such as EXCEL or participating in e-learning activities (on-demand webcasts) from accredited providers from the USA that have been certified for AMA PRA Category 1 Credits™.

Physician assistants, nurse practitioners, and nurses may participate in this educational activity and earn a certificate of completion as AAPA, AANP, and ANCC accept AMA PRA Category 1 Credits TM through their reciprocity agreements.

Educational Objectives

At the conclusion of this conference, you should be able to:
  • Identify diverse heterogeneous clinical phenotypes of ENPP1 Deficiency leading to, among others, a prognosis of GACI and ARHR2
  • Discuss clinical symptoms, side effects, and management strategies when treating the various clinical phenotypes
  • Recognize risk factors associated with calcification in GACI, and why those surviving GACI may develop ARHR2
  • Explain why OPLL may be associated with hypophosphatemic rickets
  • Assess available and emerging treatment options 

Supporter

INOZYME PHARMA